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Description
M1 microglia are more resistant to ferroptosis than M2 microglia since they have less IRP activity and cellular labile iron pool, and higher ferritin levels, which help maintain neuroinflammation, perpetuate iron dysregulation, and ferroptosis-mediated neuronal death [298, 310, 312]
doi: 10.1001/jamapsychiatry.2019.3259
Toledano and D.L
Nadph oxidases: redox regulation of cell homeostasis and disease
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Mechanisms and inhibitors of nicotinamide N-methyltransferase
