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Description
The C57Bl/6J strain, which is most often used for drug toxicity studies, has an average susceptibility to an APAP overdose [128]

For example, they could be used to treat anemia, sickle cell disease, and other blood disorders

10.3390/pharmaceutics12121235 176

Leng Y, McEvoy CT, Allen IE, Yaffe K

By contrast, hesperetin inhibits ferritinophagy and mitigates ferroptosis by modulating the PI3K/AKT/mTOR/ULK1 pathway (100), further underscoring the context-dependent role of ULK1

Nat Rev Cancer (2012) 12:40110
