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and Israeli war on Iran, which has sent global energy prices through the roof

Endoxifen is a new potent inhibitor of PKC: a potential therapeutic agent for bipolar disorder

It is characterised by a sharp increase in hydrogen ions that affect blood pH (Reference Standl and Ditzel153) , which hinders erythrocyte glycolysis, mainly through the inhibition of phosphofructokinase, which decreases 2,3-DPG

Nature 438 , 11761180 (2005)

doi: 10.1038/srep25564

Depending on stimuli, microglia can adopt distinct phenotypes: the M1 pro-inflammatory state (induced by lipopolysaccharide and characterized by production of cytokines such as TNF-, IL-1, and IL-6) and the M2 anti-inflammatory state (induced by IL-4 or IL-13, promoting repair) [122, 123]