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Mature MII oocytes contain 100,000-200,000 mtDNA copy numbers, which is positively correlated with fertilization and embryonic developmental potential [37]

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In skin, GHK-Cu signals fibroblasts to produce collagen, modulates matrix metalloproteinases for balanced tissue remodeling, and triggers expression changes in approximately 31 percent of human genes toward a younger profile 1 9

doi: 10.1098/rspb.2014.0128 74

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The second is that inhibition of NMDARs can cause persistent beneficial changes to the brain in the context of depression