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However, agonists that exclusively act on one or another receptor have not been identified as yet, and the understanding of the role of each receptor in most of the tissues in which both receptors are present is difficult

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By fusing an anti-TfR1 domain to a therapeutic antibody, these constructs achieve higher and more uniform brain distribution

Office of Dietary Supplements, National Institutes of Health

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Affolter, M., Zeller, R