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BMC Pregnancy Childbirth 20 , 80 (2020)

In some cases, individuals may suffer from both Lyme disease and mold toxicity simultaneously, further complicating diagnosis and treatment

2.1 APPLICATIONS OF THE REDOX-BASED PROTEOMICS APPROACH IN MDMA-EXPOSED TISSUES The redox-based, Cys-targeted approach using biotin-NM, as we originally described [5154], exhibited a major advantage in detecting subtle increments in the amounts of oxidatively-modified proteins over the previously existing methods of using biotin-conjugated iodoacetamide (BIAM) [60], 4-iodobutyl-triphenylphosphonium [61], or isotope-coded affinity tag (ICAT) reagent [62], mainly because the levels of oxidized proteins detected with these reagents (e.g., BIAM, 4-iodobutyl-triphenylphosphonium, or ICAT) are inversely related to the increased levels of oxidative stress