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L-Carnitine remains an important area of study across multiple fields including exercise science, mitochondrial biology, metabolism research, cardiovascular research, and healthy aging

[DOI] [PubMed] [Google Scholar] 208.Li S, Gao D, Jiang Y

61,62 One of the major limitations of this study was the low number of patients and the absence of a placebo arm, prompting a placebo-controlled AST-120 Used to Treat Mild Hepatic Encephalopathy (ASTUTE) clinical trial, 63 a multicenter, double-blind RCT that randomized 148 patients with compensated cirrhosis to receive either dose-ranging oral AST-120 (2 or 4 g three times per day) vs

This excess pathway activity causes oxidative stress and Na + /K + -ATPase dysfunction

These findings suggest a potential role of ALC in modulating cholesterol levels