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Indeed, one of the important mechanisms by which the brain connections are maintained and tuned is through synaptic pruning, whereby highly active synapses are strengthened and less active synapses are removed through axon retraction (Luo and OLeary, 2005

Burmeister WP, Gastinel LN, Simister NE, Blum ML, Bjorkman PJ

Hsieh LT-H, Frey H, Nastase M-V, Tredup C, Hoffmann A, Poluzzi C, et al

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