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Association between NNMT and Obesity Early evidence of the association between NNMT and obesity was observed in metabolomic works, of which the results show that the MNA levels in human urine are positively correlated with the body mass index (BMI) [20, 21]

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Adult male C57BL/6 mice on a 60% kcal-from-fat high-fat diet received intraperitoneal or oral 5-Amino-1MQ at amounts in the milligram-per-kilogram range or vehicle, over an 11-day treatment period in the published protocol