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Migneault, 2004)
[DOI] [PubMed] [Google Scholar] Sen CK, Khanna S, Reznick AZ, et al

Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease
Some got as high as 20%

101 ZhaoC.YangC.ZangD.LanX.LiaoS.ZhangP.et al (2017)

Aggrecan molecules link to hyaluronic acid forming massive aggregates trapping water
