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As a result, aside from its protective role in -cells, butyrate has been proposed as a direct regulator of insulin secretion via GPR-mediated signaling

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Nevertheless, exposure to pesticides could impose a serious risk to this species, especially considering its restricted distribution, habitat specificity, and high physiological demand to metabolize xenobiotics

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Our work demonstrates that CGA concentrations exceeding 600 M in vitro significantly inhibit hepatocyte growth, clonogenicity, and viability, and induce acute toxicity at high intravenous doses in vivo

Gut 67 , 13171327 (2018)