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In Denmark, however, patients receive injections of 1 mg cyanocobalamin per week during the first month and every 3 months after that, or 1 mg hydroxycobalamin every other month.

Furthermore, health risks, family history, other medications, age, and personal health factors, are also going to dictate the results you are going to see, and how quickly you can expect to see those results

XENical in the prevention of diabetes in obese subjects (XENDOS) study a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients

link Ng FM, et al

This is the bigger risk and it is the reason we insist on a written history first

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