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Multiple meta-analyses and pooled analyses of the published literature have found that low-protein diets and very-low-protein diets supplemented with nitrogen-free derivatives of essential amino acids (eg, compounds called keto-analogues or keto acids) have a range of benefits in slowing disease progression

Supplementation is an avenue that some athletes use with the intention of impacting positively on performance

Am J Clin Nutr 114(3):882-92 2021 PMC8408839 Schmidt KA, Cromer G, Burhans MS, Kuzma JN, Hagman DK, Fernando I, Murray M, Utzschneider KM, Holte S, Kraft J, Kratz M

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If excessive amounts of free fatty acids accumulate in the body, this can lead to mitochondrial damage, resulting in cells and the animals body suffering from a lack of energy

J., Lerman L