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We found that niacin intake can elevate blood NAD + levels to a maximum of 80-120 M, a four to six-fold increase from normal levels, reaching a plateau in blood with daily doses of 500-750 mg

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Miroczuk-Chodakowska I., Witkowska A.M., Zujko M.E

While it is well known that enhanced insulin sensitivity and low insulin levels are associated with an improved survival, there is evidence showing that attenuation of growth hormone/IGF-1 axis may have beneficial effects in extending lifespan in humans

Some protocols use one or the other

ERGO can bind up metal ions and remove them ERGO chelates (binds and eliminates) metal ions such as mercury, iron, copper, zinc, nickel, and cobalt (5, 8)

It accelerates re-epithelialization, supports stem cell differentiation, and improves recovery in aged or damaged tissues through increased microvessel density and modulated inflammatory pathways (e.g., NF-B and MAPK)