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Wu T, Li Y, Liu B, Zhang S, Wu L, Zhu X, et al

Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease

Cependant, ltude souligne quelle comporte des limites (en partie ralise sur les rats et sur un chantillon humain trs limit, uniquement compos d'hommes) , et indique que ses observations ne doivent pas tre prises au pied de la lettre

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As Rv0884c is an essential gene for the viability of the cell 24,25 , we used a well-established CRISPR interference method 26 to generate an anhydrotetracycline (ATc)-inducible, Rv0884c-knockdown (Rv0884c_cKD Tet ) Mtb H37Rv strain (Extended Data Fig

Mitochondria morphological changes are associated with dysfunction and altered energy metabolism, whereby adenosine triphosphate (ATP) production is insufficient to maintain the Na+/K+-ATPase neuronal activity, which leads to massive calcium (Ca +2 ) influx followed by glutamate toxicity [24]