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Surg Endosc 2002;16:1362

Reduction of Hyperpigmentation Whether caused by sun exposure, hormonal changes, or acne scars, hyperpigmentation can make the skin look patchy and dull

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We used the contour-enhanced funnel plots to assess publication bias, if 10 or more trials were available for an outcome (Harbords test for dichotomous outcomes and Eggers test for continuous outcomes) [23, 24]
