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[15] In hepatocytes, compounds undergo enzymatic transformation in two main phases: Phase I reactions (often mediated by cytochrome P450 enzymes) introduce functional groups, and Phase II reactions conjugate these compounds to increase water solubility and facilitate elimination

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the subject in need thereof may be a subject identified as being a responder based on: [1] the subject having autism or ASD and having lower plasma and/or intracellular levels of GSH, tGSH, or both, as compared to a control group without a diagnosis of autism or ASD

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Its molecular composition allows for detailed analysis in experimental frameworks focusing on peptide stability, metal-binding dynamics, and molecular modeling