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xCT, system Xc

Areas of active hepatocellular degeneration and/or necrosis often present

Interestingly, it was recently shown that the marine invertebrate Amphioxus expresses a non-selenoprotein that deiodinates Triac but not T3 (29)

Taken together, these findings support the concept that fecal butyrate may serve as a complementary biomarker of mucosal healing and treatment response, and further position MSB as a promising therapeutic adjunct in UC, warranting continued investigation in larger and longer-term clinical trials

Immunostaining of brain tissue for Iba1 and GFAP revealed that microglia and astrocytes were markedly activated in GCLC-KO mouse brains (Fig