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Description
The first step consists of the oxidation of the reduced GPX enzyme hydroperoxide-type compound, while the second step is a series of reductions of the oxidized GPX enzyme by a thiol-containing compound such as the reduced cofactor glutathione (GSH)

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C.Martins MdeL.ChanK

First, glutamate-cysteine ligase (GCL) catalyzes the conjugation of cysteine and glutamate, which results in the formation of \(\gamma\)-glutamylcysteine