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Risk of hepatocellular carcinoma A systematic review and meta-analysis of 25 adult studies including 6528 patients followed for a median of 8 years showed that incidence of hepatocellular carcinoma in AIH is 3.06 per 1000 patient-yearsthis rate increases with presence of cirrhosis at diagnosis of AIH (10.07 per 1000 patient-years) [164]

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