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Upon white light irradiation, AIEgen TPA-S-TPP generated a high dose of 1 O 2 in the mitochondria of cancer cells, resulting in a decrease of the m and release of cytochrome c , which activated the caspase-3 activity and induced apoptosis

Data availability Computer code for LSA, parameter estimation, numerical simulations, and GSA with PRCC was implemented in and run with the programming and computation software MATLAB (MathWorks Inc., Natick, MA, USA)

These factors can all contribute to the HIF stabilization under normoxic conditions in tumors and should be considered for future therapeutic approaches

Several cases of Mninduced Parkinsonism have been reported in individuals whose professions involve prolonged contact with high atmospheric levels of Mn such as welders, miners and smelters (Rodier, 1955
Compared with the wild type (WT) protein, K240A exhibits an increased k cat toward tyrosine and a decreased k cat toward DOPA
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