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Al-Hakeim, H
J Cell Biol 165, 723734
Therapeutic drugs mainly include statins and anti-diabetic agents as well as metformin, which also exert anti-inflammatory effects
A breakthrough study by Rosen and others (Rosen et al., 1993) recognized that the SOD1 gene-associated mutations encode for the 2% of ALS and 20% of familial amyotrophic lateral sclerosis (FALS) cases (Gamez et al., 2006)
50.Bjrklund G, Tinkov AA, Hosnedlov B, et al
SAMe was shown to inhibit PS1 promoter demethylation and thereby downregulated the PS1 mRNA expression in SK-N-SH human neuroblastoma cells, which resulted in a lowered secretion of A [140]
