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Organic cation transporter 2 (OCT2), situated on the basolateral membrane of renal tubular cells, serves as a crucial uptake transporter for TMAO, with over 90% of TMAO being excreted in the urine after renal metabolism ( via faeces, and less than 1% is expelled through respiration

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Remarkably, NT1 compared to NT2 patients report shorter sleep lengths during the weekend (Sleep.length.weekend) (7.97 0.08 h vs

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Our study has several limitations

Within these pathways, many cell cytokines, including those associated with inflammation, such as IL-1, IL-6, TNF-10, IL-22, and TNF-alpha, contribute to the anorexia of cancer patients [8, 9, 12]