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Post-Exertional Malaise (PEM) and Fatigue: Alpha lipoic acid and sulforaphane help protect the mitochondrial electron transport chain from superoxide radical damage, supporting more efficient ATP (energy) production and potentially raising the threshold for exertion-induced crashes

DrugBank lists various GST inhibitors (Table 2) that are in investigational, experimental stage or approved by the US FDA

Any athlete subject to WADA-compliant testingincluding Olympic, NCAA, and many professional league athletesfaces a four-year suspension for a first violation

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