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Myofibroblasts, characterized by enhanced proliferation and migration capabilities, secrete numerous cytokines and ECM, expressing proteins like alpha-smooth muscle actin (-SMA), contributing to damage repair (Hinz and Lagares, 2020

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PQQ reduces the oxidative stress to safeguard heart muscle cells, oxidizes the redox site of N-methyl-D-aspartate (NMDA) receptor, enhances thymidine integration into fibroblasts, inhibits melanin production in murine B16-F10 melanoma cells while boosting the production of nerve growth factors (NGF) (He et al., 2003