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In the blood, the enriched pathways included long-term depression, melanogenesis, protein digestion and absorption, glutamatergic synapses, central carbon metabolism in cancer, the FOXO signaling pathway, cocaine addiction, neuroactive ligandreceptor interactions, and arginine and proline metabolism (Fig

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Carnitine supplementation during VPA therapy in high-risk patients is now recommended by some scientific committees and textbooks, especially paediatricians

However, supplemental iron should not be taken without confirmed deficiency, as excess iron is pro-oxidant and can impair fertility

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