glutathione colon cancer Cysteine Regulates Oxidative Stress and Glutathione-Related Antioxidative Capacity before and after Colorectal Tumor Resection Mollugin suppresses proliferation and drives

Many mechanisms have been proposed to explain MDR, such as the decrease in intracellular drug concentrations due to efflux pump induction, the mutation of drug targets, the upregulated metabolic detoxification, and the enhanced DNA damage repair function [63]

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10.1080/19420889.2017.1356956 [DOI] [PMC free article] [PubMed] [Google Scholar] 187.Zhang X, Zhang N, Chrenek MA, Girardot PE, Wang J, Sellers JT, et al

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Interestingly, the mutation rate of H274Y (A(H1N1) pdm09 high-frequency mutation site) in 2009 was lower than that in 2008, indicating that the ancestral strain of A(H1N1) pdm09 may have spread to humans in the months before this outbreak [78]