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however, in phase 1 clinical trial, BIIB078 failed to exert meaningful effects on CNS pathologies and had no significant impact on neurofilament levels but paradoxically increased inflammatory marker CCL26, and its development has been discontinued (van den Berg et al., 2024

doi: 10.1021/jm0700969 60 GanzT

The Vasculature and its Role in the Damaged and Healing Tendon
