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31 The methanol extract of Jamun fruits inhibited the formaldehyde, carrageenan, and prostaglandin E2-induced paw edema in mice as well as in vitro , whereas 50% methanol and dichloromethane extract showed weak anti-inflammatory activity
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Upon mPTP opening, cytochrome c (Cyt c) is released from the mitochondrial intermembrane space into the cytosol, initiating the intrinsic (mitochondrial) apoptotic pathway

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Previously unreported effects of RSL3, such as degradation of mTOR signaling pathway protein, p70S6K, and reduction of p-NPM1 levels were identified in the present study and warrant further investigation

doi: 10.1177/2633105520907895, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Ross D
