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doi: 10.3389/fphar.2022.910292 Received 01 April 2022 Accepted 03 August 2022 Published 29 August 2022 Volume 13 - 2022 Edited by Seung-Yeol Park, Pohang University of Science and Technology, South Korea Reviewed by Amit Krishna De, Indian Science Congress Association, India Jinke Wang, Southeast University, China Updates Copyright 2022 Li, Long, Zhou, Luo, Xu and Gao

J Plant Physiol 148:391398 Foyer CH, Lopez-Delgado H, Dat JF, Scott IM (1997) Hydrogen peroxide and glutathione-associated mechanisms of acclimatory stress tolerance and signalling

Neutrophils and macrophages infiltrating the inflamed gut release excessive ROS and cytokines such as TNF- and IL-1, exacerbating oxidative stress and amplifying ferroptosis-induced tissue injury (171)

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Combination therapy increases cost/time but offers higher durability