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Interestingly, animal model studies employing dietary choline or TMAO, germ-free mice and microbial transplantation confirmed a role for gut microbiota-dependent TMAO production in modulating platelet hyperresponsiveness and thrombotic potential (78)

As a consequence, treatments have been directed towards treating the symptoms rather than the cause

Therefore, PAI-1 secreted by BMAds within the bone marrow niche may only inhibit hematopoietic regeneration after HSC transplantation without directly affecting mobilization

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Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes

studied the changes in GS messenger ribonucleic acid of mononuclear cells in peripheral blood after exercise in healthy volunteers