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Thrombotic risks associated with JAK inhibitors require careful monitoring in diabetic populations with preexisting cardiovascular comorbidities

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Higher doses do not improve senolytic efficacy but increase the risk of transient side effects like localized injection site inflammation

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PubMed Thomas, M.K., Nikooienejad, A., Bray, R., Cui, X., Wilson, J., Duffin, K., et al