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Two trials reported data for serum vitamin B 12 levels

When you stop taking 5-amino-1MQ, NNMT activity gradually returns to baseline levels over several weeks

Research suggests people with low B12 levels are more likely to experience migraine compared to those with higher levels

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Persistent fatigue, brain fog, low mood, weight gain, tingling in the hands or feet, frequent illness, post-COVID fatigue, or feeling generally "off" despite eating well and sleeping enough, especially if you're vegetarian, vegan, over 50, on metformin or a long-term acid reflux medication, or have a history of low B12 or pernicious anemia