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A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use in generally healthy adults

doi: 10.1530/RAF-21-0123 22 LiJJLiuLYWengJYinTLYangJFengHL

Nature Communications 2021 12:1 (Vol

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There is also evidence that PCSK9 induces the degradation of other LDLR-related proteins, such as very low-density lipoprotein receptor (VLDLR),apolipoprotein E receptor 2 (ApoER2), (Poirier et al., 2008), and LDLR-related protein 1 (LRP-1) (Canuel et al., 2013), as well as the unrelated fatty acid receptor CD36 (Demers et al., 2015)