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Any disagreement was resolved by consensus with other coauthors
PMID 23945587

Ligand-activated PPAR can inhibit NF-B signaling by impeding p65 nuclear translocation and reducing p65/PPAR complex formation ( Clinical evidence supports these anti-inflammatory effects

Trimethylamine-N-oxide promotes vascular calcification through activation of NLRP3 (Nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome and NF-B (Nuclear factor B) signals

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