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The study reported a confirmed ORR of 35.8%, which included four complete responses (CR) and 45 partial response, alongside 56 instances of stable disease

Criteria for necrosis included karyorrhexis (loss of nucleus) and/or degeneration of cytoplasm with either coagulative or liquefactive changes

Behav Sleep Med

The final analyses were conducted with 15 subjects in the LD group and 15 subjects in the HD group

Pediatr Endocrinol Rev 5:766771 Laron Z, Silbergeld A, Klinger B (1998) Hyperandrogenism induced by insulin-like growth factor-I (IGF-I) treatment of two girls with Laron Syndrome

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