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Small pilot studies have indicated that intranasal insulin administration is a feasible treatment modality that can enhance cognitive functions, including delayed verbal memory and attention (133), offering a potential approach for addressing neurodegenerative disorders and cognitive decline

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study had a clinical profile resembling autoimmune lymphoproliferative syndrome (ALPS), hemophagocytic lymphohistiocytosis (HLH), and autoimmune hemolytic anemia (AIHA) with expanded CD21 low CD38 low B cells (126128, 241)

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