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Consequently, SP@M could domesticate SMs into an anti-inflammatory phenotype of M2-like, and suppress synovial inflammation in vivo (Fig

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The DOCA-salt model is relevant to human hypertension as it involves an hypervolemia, an activation of the sympathetic nervous system and the suppression of the peripheral RAAS system, and thus a low renin hypertension, which is observed in ~32 % of the hypertensive population (422)

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