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Some specific short-term protocols even use up to 2000 mg without significant adverse effects

GH peak values were higher in DM 1 patients than in control volunteers, after GHRH (52.2+/-9.8 vs

85 (8_Suppl
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2024;16(732):eadg8357

In tissues where GHS-R1b is highly expressed relative to GHS-R1a, the GH-releasing efficacy of Ipamorelin may be reduced due to this heterodimerization-mediated dampening effect
