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In this study, we demonstrated that Np63 regulates GSH, which scavenges ROS and is generated from serine and glycine, in a NRF2-dependent manner
95 , 96 In parallel, exosome-mediated activation of the PI3K/Akt pathway suppresses apoptosis-related effectors such as Caspase-3, thereby improving cell viability and tissue integrity
Modifier locus on mouse chromosome 3 for renal vascular pathology in AT1A receptor-deficiency
& Shao, Z
In contrast, taltrimide treatment significantly promoted seizures, displaying proconvulsant activity in humans
Ballard-Croft C, Wang D, Sumpter LR, Zhou X, Zwischenberger JB
