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Network toxicology identified the underlying mechanisms by which PFAS may influence atherosclerosis or hyperlipidemia The two-dimensional structures of the four PFAS are shown in Figure S13A-D

Complementary in vitro assessments further indicate that luteolin exhibits minimal cytotoxicity toward non-malignant cells at concentrations typically required for anti-inflammatory or antioxidant actions, supporting a favorable biological response profile (Tuli et al., 2022)

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This has been particularly well-studied in conventional dendritic cells (cDCs)

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[DOI] [PubMed] [Google Scholar] 68.Zhuang X, Xiang X, Grizzle W, Sun D, Zhang S, Axtell RC, et al