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If you develop signs of high cortisol like central weight gain despite overall weight loss, morning headaches, or mood disturbances, testing cortisol through saliva or 24-hour urine collection may be appropriate

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Journal of Nutritional and Environmental Medicine 2007 16:3-4, 212-226 doi=10.1080%2F13590840701791863 Catherine S

When this process is disrupted, a structural problem called a neural tube defect can occur

When certain nutrients are deficient, serotonin, dopamine, and GABA production suffer