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References Kalluri R, Weinberg RA

DCHD can effectively improve pancreatic fibrosis by inhibiting the infiltration of pancreatic macrophages and the secretion of inflammatory factors ( Sulindac is an aryl chain acid non-steroidal anti-inflammatory drug that is reversibly converted to sulindac sulfide, an anti-inflammatory active compound in the body that inhibits COX-1 and COX-2 activities, reduces prostaglandin(PG) synthesis, and exerts analgesic and anti-inflammatory effects (116)

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Intestinal microbiome diversity of diabetic and non-diabetic kidney disease: current status and future perspective