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Wahibah et al., 2018)

In the case of nitrogen, this effect is partly driven by the increased demand in glutamate to sustain photorespiratory metabolism due to both the direct involvement of 2-oxoglutarate/glutamate cycling and the slight incompleteness of glycine-to-serine production, which must be compensated for by an increased N assimilation 37

Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients

Instead, it appears to influence multiple brain systems involved in sleep regulation and stress

N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial