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M., Heck, S

J., Yang, H

TGR inhibitors do not react covalently with GSH, selenocysteine, or TGR, and inhibition of TGR is reversible To evaluate stability of the TGR inhibitors in the presence of GSH and selenocysteine, compound 2 and a known covalent inhibitor of TGR, TRi-1 20,45 , were incubated with GSH or the N-Boc protected methyl ester of selenocysteine, and the reaction mixtures were analyzed by LCMS (Supplementary Figs

To that purpose, like most holdases, CnoX transfers its substrates to ATP-dependent foldases (Goemans et al., 2018b)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Martin KA, Anderson RR, Chang RJ, Ehrmann DA, Lobo RA, Murad MH, Pugeat MM, Rosenfield RL
