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For a detailed understanding of the key regulatory factors in the ferroptosis-related pathway, including GPX4, System Xc-, NRF2, ACSL4, Coenzyme Q10, FSP1, and p53, refer to Fig

Middelkoop E, Wiemer EA, Schoenmaker DE, Strijland A, Tager JM (1993) Topology of catalase assembly in human skin fibroblasts
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1986) and humanization of the reaction specificity of mouse Alox15 leads to dysregulated erythropoiesis (Reisch et al
E.YangL.et al (2006)

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