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The antidiabetic drug metformin , amino acid derivative carnosine, and B-vitamin derivatives benfotiamine and pyridoxal-5-phosphate are examples of agents that mitigate glycation- and AGE-related tissue damage (Ceriello 2009

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It also includes small quantities of red wine

Future research should focus on clinical validation, dose optimization, and the development of effective delivery systems to improve stability and bioavailability