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This negative effect of nicotinic acid is the result of the activation of HCA 2 on macrophages

Regulation of CBS The haem cofactor in the Nterminal domain of CBS can bind CO or NO, which can inhibit its activity (Singh et al ., 2007)

doi: 10.1038/nrn2755

Histamine Histamine is a monoamine neurotransmitter that contributes to the regulation of fundamental bodily functions, including the sleep-wake cycle, energy-endocrine homeostasis, synaptic plasticity, and learning

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These findings suggest that specific plant-based dietary components protect against cognitive decline and support the rationale for a plant-rich diet
