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It helps neutralize free radicals, preventing cellular damage and reducing the risk of chronic diseases, such as cancer, heart disease, and neurodegenerative disorders

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Costunolide inhibits pulmonary fibrosis via regulating NF-kB and TGF- 1 /Smad 2 /Nrf 2 -NOX 4 signaling pathways

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Pediatr Nephrol 14(7):589597 Tonshoff B, Kiepe D, Ciarmatori S (2005) Growth hormone/insulin-like growth factor system in children with chronic renal failure