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As expected, these mice exhibited markedly increased BAC after receiving a high dose of alcohol by gavage, and this increase was associated with more hepatic endoplasmic reticulum (ER) stress, hepatocyte apoptosis, and lipolysis

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As this does not mirror the clinical efficacy observed for efgartigimod within CIDP, and as the used FcRn antagonist did reduce total levels of circulating IgG to an extent beyond that observed for IVIg treatment, it must be because of this animal model being driven by other mechanisms than solely autoreactive IgG

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